Clinical Presentation


Signalment

  • young to young adult captive lions

History

  • progressive neurologic abnormalities
  • blood work, ultrasound usually normal
  • delayed growth
  • death of young cubs and stillbirth

Initial presentation

  • ataxia
  • weakness
  • moderate dementia or depression
  • reluctance to move
  • reduced appetite
  • seizures

Findings on neurological examination

  • pronounced weakness
  • unstable hypermetric gait
  • progressive ataxia
  • uncontrollable head movements and head posture
  • tremors
  • head tilt
  • abnormal cranial nerves function manifested as hyper salivation, protrusion of the tongue
  • inability to stand or walk
  • head pressing
  • opisthotonos
  • death

Neuro-anatomical localization

Neurological examination findings lead to localizing the lesion to the cerebellum, medulla, and the cranial segment of the spinal cord. Forebrain signs are usually a result of increased intracranial pressure due to compromised cerebrospinal fluid drainage.

About us
Merav Shamir
Rona Nadler

Imaging
CT imaging
MRI Imaging
Radiographs
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Publications
References