huji Koret School of Veterinary Medicine

Robert H. Smith Faculty of Agriculture, Food and Environment,
The Hebrew University of Jerusalem

Merav H Shamir, BSc., DVM

Dipl. ECVN
Professor of Veterinary Neurology & Neurosurgery
Head of neurology service, The Veterinary Teaching Hospital,
Head of the curriculum committee - Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food & Environment, The Hebrew University of Jerusalem.

Please Visit Our New Site:

Clavarial Hyperostosis in Lions (Panthera leo) Research Group

to learn more about neurological diseases in lions, in particular, diagnosis, treatment and prevention of Clavarial hyperostosis.
Vitamin A deficiency is believed to be the underlying cause, but genetic and other environmental factors may predispose some to develop abnormal bone growth.

Office Address:
P.O. Box 12, Rehovot 76100, Israel
Phone: +972-(0)3-9688558
Fax: +972-(0)3-9604079
Email Address:

Special interests

Veterinary neurology neurosurgery, wild animal neurology.

Professional Experience and Qualifications

Diplomat of the European College of veterinary neurology, Specialist in small animal surgery - Israeli college of veterinary surgeons.


Veterinary neuro-anatomy, neurobiology, neurological examination and clinical neurology and neurosurgery.



Pathophysiology of neurological diseases. Pathophysiology of seizures in the dog. Clavarial Hyperosteosis in lions



Head of curriculum committee, Koret School of Veterinary Medicine.


International interests

Member of the education committee, the European college of veterinary neurology.


Membership in Scientific organizations

- European society of veterinary neurology.


Selected Recent Publications

Chamisha, Y, Aroch I., Kuzi S, Srugo I., Bdolah-Abram T., Chai O., Christopher MM., Merbl Y., Rothwel K., Shamir MH. (2015) The prognostic value of cerebrospinal fluid characteristics in dogs without deep pain perception due to thoracolumbar disc herniation. Research in Veterinary Science.

Merbl, Y., Sommer,A., Chai.O., Aroch, I., Zimmerman,G., Friedman,A., Doreq,H. and Shamir, H.M. (2014) Tumor necrosis-α and interleukon-6 concentrations in Cerebro-Spinal Fluid of dogs following seizures J Vet Intern Minor Corrections, Corrected and re-submitted.

Barnoon, I., Shamir, H.M., Aroch, I., Bdola-Abram, T., Chai, O., (2014) Evaluation of combined mycophenolate mofetil and prednisone treatment for meningoencephalomyelitis of unknown etiology in dogs: 25 cases (2005-2011). JVet Emerg Critical Care, In press (1.528, 33/143;0)

Saragusty, J., Nadler, R., Shavit-Meyrav, A ., Yamaguchi,N., Bdolah-Abram, T., Gibeon, L., Shamir, H.M. (2014). Comparative Skull Analysis Suggests Species- Specific Captivity-Related Malformation in Lions (Panthera leo). PLOS One, In Press

Chai, O., Sommer, A., Zimmerman, G., Soreq, H., Friedman, A., Bdolah-Abram, T., Aroch, I., and Shamir, H.M. (2013). Acetylcholinesterase activity in the Cerebro-Spinal Fluid of Dogs with Seizures. Vet J,;198:292-4. (2.424;4/143;0)

Shamir, H.M., Rubin, G., Aizenberg, Z., Berkovitz, Z,. Reifen, R., Horowitz, I., Bdolah-Abram, T., and Aroch, I., (2012). Needle biopsy for hepatic vitamin A levels in lions (Panthera Leo). J. Zoo Wildl Med. 43:207-13. (0.427;100/143;0)

Dadon- Nachum, M., Ben- Zur, T., Srugo, I., Shamir, H.M., Melamed. E., Yaffe, D., and Offen, D., (2012). Therapeutic effect of genetically modified muscle progenitor cells in a rat model of sciatic nerve injury. J. Stem Cells & Reg. Med. 8;21-27 (This journal is not included in the ISI list)

Srugo, I., Aroch, I., Christopher, M.M., Chai, O., Goralnik, L., Bdolah-Abram, T., Shamir, H.M. (2011). Association of cerebrospinal fluid analysis findings with clinical signs and outcome in acute non-ambulatory thoracolumbar disc disease in dogs. J Vet Intern Med. ;25:846-55. (1.992;15/145;3)

Roth, J., Shtokman, J., Shamir, H.M., Nissan, M., Shchetinkov, L., Trejo, L.L., Rochkind, S., (2011). Regeneration of the transected rat sciatic nerve after suturing or adhesion with cyanoacrylate glue. J Neurosurg; 114: 245-252. (2.965;24/199;2)

Aroch, I., Keidar, I., Himelstein, A., Schechter, M., Shamir, H.M., Segev, G. (2010). Diagnostic and prognostic value of serum creatine-kinase activity in ill cats: a retrospective study of 601 cases. J Feline Med Surg. ; 12:466-75. (1.681; 21/145;1)


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