huji Koret School of Veterinary Medicine

Robert H. Smith Faculty of Agriculture, Food and Environment,
The Hebrew University of Jerusalem

Michael J. Gutnick, DVM, Ph.D

Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food & Environment, The Hebrew University of Jerusalem.

Office Address:
P.O. Box 12, Rehovot 76100, Israel
Phone: 972-8-9489875, 054-8820152
Fax: 972-8-9489876
Email Address:

Special interests

Cellular Physiology of the Cerebral Cortex in Health and Disease, Pathophysiology of Epilepsy, Biophysical properties of ion channels in the central nervous system

Professional Experience and Qualifications

DVM, 1967, University of California at Davis

Ph.D. (Neuroscience), 1972, Stanford University


Animal Physiology, Veterinary Physiology, Fundamentals of Neural Circuit Function



sodium channels, neocortical neuron, excitability, synaptic integration, axon, basal dendrites, polyamines, Na imaging, epilepsy



Reviewer for Journal of Neuroscience, Journal of Neurophysiology, Journal of Physiology, Cerebral Cortex etc., grant applications for BSF, ISF, GIF, National Institute for Psychobiology, Israel Ministry of Science,


International interests

Collaborations with Max-Planck-Institute for Dynamics and Self Organization, Goettingen, Germany; New York Medical College


Membership in Scientific organizations

- Israel Society for Neuroscience
- American Society for Neuroscience


Selected Recent Publications

Fleidervish I.A. , Libman L. , Katz E. , Gutnick M. J. (2008) Endogenous polyamines regulate cortical neuronal excitability by blocking voltage-gated Na channels. Procedings of the National Academy of Sciences of the USA (PNAS) 105: 18994-9
Astman N., Gutnick M. J., Fleidervish I.A. (2006) Persistent sodium current in Layer 5 neocortical neurons is primarily generated in the proximal axon. Journal of Neuroscience 26: 3465-73
Binshtok A.M., Fleidervish I.A., Sprengel R., Gutnick M.J. (2006) NMDA receptors in Layer 4 spiny stellate cells of the mouse barrel cortex contain the NR2C subunit. Journal of Neuroscience 26: 708-715
Levavi-Sivan B., Bloch C.L., Gutnick M.J., Fleidervish I.A. (2005) Electrotonic coupling in the anterior pituitary of a teleost fish. Endocrinology 146: 1048-1052



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